Migliorini is a surname. Notable people with the surname include:
Andrea Migliorini (born 1988), Italian footballer playing for Melbourne HeartBarry Migliorini (born 1966), American Professional Basketball CoachBruno Migliorini (1896–1975), Italian linguist and philologistGiovanni Migliorini (born 1931), retired Italian professional football playerMarco Migliorini (born 1992), Italian footballer playing for TorinoRenato Migliorini (1926–2008), Brazilian physician, biomedical scientist, biochemist and full professor of physiology