Middlebrooks is a surname. Notable people with the name include:
C. Edward Middlebrooks (born 1955), American politician from MarylandDonald M. Middlebrooks (born 1946), United States District Court judgeDavid Lycurgus Middlebrooks, Jr. (born 1926), United States federal judgeFelicia Middlebrooks (born 1957), American radio news broadcasterLevy Middlebrooks (born 1966), American basketball playerWill Middlebrooks (born 1988), American professional baseball playerWillie Middlebrooks (born 1979), American gridiron football playerWindell Middlebrooks (1979–2015), American actor and singer