Middlebrooks is a surname. Notable people with the name include:
C. Edward Middlebrooks (born 1955), American politician from Maryland
Donald M. Middlebrooks (born 1946), United States District Court judge
David Lycurgus Middlebrooks, Jr. (born 1926), United States federal judge
Felicia Middlebrooks (born 1957), American radio news broadcaster
Levy Middlebrooks (born 1966), American basketball player
Will Middlebrooks (born 1988), American professional baseball player
Willie Middlebrooks (born 1979), American gridiron football player
Windell Middlebrooks (1979–2015), American actor and singer
