Micheli is an Italian surname. Notable people with the surname include:
Amanda Micheli, American filmmaker
Blessed Clotilde Micheli (1849-1911), Italian Roman Catholic professed religious
Dante Micheli (1939–2012), Italian footballer
Franco Micheli, Italian sports shooter
Giuseppe Micheli (1888–?), Italian modern pentathlete
Guglielmo Micheli (1866-1926), Italian painter
Ivo Barnabò Micheli (born 1942), Italian film director and screenwriter
Jacques-Barthélemy Micheli du Crest (1690–1766), Genovese politician, physicist and cartographer
Lucia Micheli (born 1969) - Italian sprint canoer
Pier Antonio Micheli (1679–1737), Italian botanist, abbreviated as "P.Micheli"
Marc Micheli (1844–1902), Italian botanist, abbreviated as "Micheli"
Maurizio Micheli (born 1947), Italian actor, voice actor, author and playwright
Rodolfo Micheli (born 1930), former Argentine football striker
Ron Micheli (born 1948), former director of the Wyoming Department of Agriculture (1977-1992)
Zanetto Micheli (c. 1489–after 1560), Italian, the first representative of the oldest known family of string instrument makers