Michaelis or Michelis is a surname, and may refer to:
Adolf Michaelis, German classical scholar
Anthony R. Michaelis, German science writer
Edward Michelis, German theologian
Georg Michaelis, German politician
Gustav Adolf Michaelis, German obstetrician
The rhombus of Michaelis named after him
Hans-Thorald Michaelis, German historian
Johann David Michaelis, German biblical scholar
John H. Michaelis, American four-star general
Laura Michaelis, American linguist
Leo Michelis, Greek economist
Leonor Michaelis, German scientist known for Michaelis–Menten kinetics
Max Michaelis, South African financier
Margaret Michaelis-Sachs, Austrian-Australian photographer
Paul Charles Michaelis, American Bell Labs scientist
Peter Michaelis, German botanist
Sebastien Michaelis, French inquisitor and writer of Michaelis' classification of demons
Sebastian Michaelis, the demon butler from Kuroshitsuji
Susanne Maria Michaelis, linguist
