Mišić is a Serbian, Bosnian and Croatian surname, derived from the male given name Mišo, or from the singular meaning "muscle". It may refer to:
Alojzije Mišić (1859–1945), Bosnian Croat Catholic bishop
Bojan Mišić (born 1978), Serbian footballer
Božidar Mišić (born 1902), first Serbian professional watch maker
Biljana Mišić (born 1983), Serbian actress
Janko Mišić (1900–1929), Yugoslav politician
Josip Mišić (born 1986), Croatian footballer
Josip Mišić (born 1994), Croatian footballer
Milana Misic (born 1970), Finnish singer of partly Croatian descent
Petar Mišić (born 1994), Croatian footballer
Siniša Mišić (born 1961), Serbian historian
Živojin Mišić (1855–1921), Serbian and early Yugoslav general
Živorad Mišić (born 1986), Serbian footballer
