Kalpana Kalpana (Editor)

Methorphan

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ATC code
  
None

PubChem CID
  
3008

UNII
  
8YB8F78WM1

CAS Number
  
510-53-2

ChemSpider
  
2901

Methorphan

Legal status
  
CA: Schedule I DE: Anlage I (Controlled) UK: Class A US: Schedule II UN: Psychotropic Schedule I

Methorphan comes in two isomeric forms, each with differing pharmacology and effects:

  • Dextromethorphan - An over-the-counter cough suppressant, as well as dissociative hallucinogen.
  • Levomethorphan - A potent opioid analgesic that was never clinically developed; the codeine analogue of the powerful opioid agonist analgesic levorphanol (Levo-Dromoran).

    • Racemethorphan refers to the racemic mixture of both of these stereoisomers. It is listed under the Single Convention on Narcotic Drugs 1961 and is therefore listed in the United States as a Controlled Substance, specifically as a Narcotic in Schedule II with an ACSCN of 9732 and an annual aggregate manufacturing quota of 3 grammes in 2014. The salts in use are the hydrobromide (free base conversion ratio 0.770) and the tartrate (0.644)

    References

    Methorphan Wikipedia
    (Text) CC BY-SA