Neha Patil (Editor)

Mesoridazine

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Trade names
  
Serentil

Routes of administration
  
Oral, intravenous

Molar mass
  
386.576 g/mol

Protein binding
  
4%

MedlinePlus
  
a682306

ATC code
  
N05AC03 (WHO)

CAS ID
  
5588-33-0

Mesoridazine

AHFS/Drugs.com
  
Micromedex Detailed Consumer Information

Pregnancy category
  
US: C (Risk not ruled out)

What does mesoridazine mean


Mesoridazine (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine. The drug's name is derived from the methylsulfoxy and piperidine functional groups in its chemical structure.

It has central antiadrenergic, antidopaminergic, antiserotonergic and weak muscarinic anticholinergic effects.

Serious side effects include akathisia, tardive dyskinesia and the potentially fatal neuroleptic malignant syndrome.

Mesoridazine was withdrawn from the United States market in 2004 due to dangerous side effects, namely irregular heart beat and QT-prolongation of the electrocardiogram.

It currently appears to be unavailable worldwide.

References

Mesoridazine Wikipedia