EC number 3.4.23.45 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 447457-31-0 BRENDA BRENDA entry KEGG KEGG entry | |
Memapsin 1 (EC 3.4.23.45, beta-secretase, beta-site Alzheimer's amyloid precursor protein cleaving enzyme 2 (BACE2), ASP1, Down region aspartic protease) is an enzyme. This enzyme catalyses the following chemical reaction
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu!Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein
This enzyme belongs to the peptidase family A1.
References
Memapsin 1 Wikipedia(Text) CC BY-SA