Melton is a surname. Notable people with the surname include:
Barry Melton (born 1947), musician and co-founder of Country Joe and The Fish
Douglas A. Melton (born 1953), developmental biologist
Florence Melton (1911–2007), American inventor
Frank Melton (died 2009), former mayor of Jackson, Mississippi
J. Gordon Melton (born 1942), American religious scholar
John Melton (died 1640), English politician and author
Justin Melton (born 1987), Filipino-American professional basketball player
Mitchell Melton (1943–2013), American politician
Parvati Melton (born 1989), Indian model and actress
Sid Melton (born 1920), American actor
Terrence Melton (born 1977), American football player
William Melton (died 1340), Archbishop of York
Matthew Melton (Born 1982) garage rock musician and producer