Mel is a surname. Notable people with the surname include:
Mele Mel (born Melvin Glover in 1961), hip-hop musician and songwriterPepe Mel (born 1963), Spanish retired footballer and current manager of Real BetisAshantha de Mel (born 1959), Sri Lankan former cricketerHenry De Mel (1877–1936), Ceylonese industrialist and politicianLakdasa De Mel, first Bishop of Kurunegala, Sri Lanka, and son of Henry De MelRonnie de Mel, Sri Lankan politician and civil servantRoyce de Mel, first Sri Lankan commander of the Sri Lanka NavyRuby de Mel (died 2004), Sri Lankan actressSamantha de Mel (born 1965), Sri Lankan-born Italian former cricketerRinaldo del Mel (probably 1554 – c. 1598), Franco-Flemish composer