Harman Patil (Editor)

Mecasermin

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AHFS/Drugs.com
  
Monograph

ATC code
  
H01AC03 (WHO)

CAS Number
  
68562-41-4

Routes of administration
  
Subcutaneous

Legal status
  
US: ℞-only

Pregnancy category
  
US: C (Risk not ruled out)

Mecasermin (INN) (trade name Increlex) is recombinant human insulin-like growth factor 1 (IGF-I), which is used for the long-term treatment of growth failure in children with severe primary IGF-I deficiency.

This drug is not to be confused with mecasermin rinfabate (trade name Iplex), which is a combination of recombinant human IGF-1 (rhIGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3). IGFBP-3 serves to prolong the action of IGF-1 in the human body.

References

Mecasermin Wikipedia