Mearns is a surname. Notable people with the surname include:
David Mearns (born 1958), a United States-born marine scientist
Edgar Alexander Mearns (1856–1916), American ornithologist and field naturalist
Frederick Mearns (1879–1931) a British footballer
Ian Mearns a British Labour Party politician
Randy Mearns (born 1969) is a Canadian former lacrosse player
Sara Mearns, New York City Ballet principal dancer
William Hughes Mearns (1875–1965), American educator and poet