McQuade is a surname. Notable people with the surname include:
Arthur McQuade (1817–1884), Irish-born Canadian politician from Ontario
Barbara McQuade (born 1964), United States Attorney for the Eastern District of Michigan
Denis McQuade (born 1951), Scottish footballer
John McQuade (1912–1984), Northern Ireland politician and professional boxer
Kris McQuade (born 1952), Australian actress
Marian McQuade (born 1917), American activist to establish National Grandparents Day
Scott McQuade (born 1962), head of communications at United Nations Volunteers
