McKeon and MacKeon are an Irish surnames originating both from the Gaelic Mac Eoghain ("Son of Eoghan") and Mac Eoin ("Son of John"), which are pronounced identically. Other variants in English include MacEoin and McKeown.
and may refer to
Alistair McKeon, fictional character in the Honorverse
Howard McKeon, American politician
Jack McKeon, American baseball manager
John McKeon (1808-1883), New York lawyer and politician, U.S. Representative
John F. McKeon, American politician
Larry McKeon, American politician
Lindsey McKeon, American actress
Matt McKeon, American soccer player
Matthew McKeon, U.S. Marine
Michael McKeon, American journalist
Myles McKeon, Roman Catholic bishop
Nancy McKeon, American actress
Philip McKeon, American actor (and brother of Nancy McKeon)
Richard McKeon, American philosopher
Stephen McKeon, film music composer