McIntire is a surname. Notable people with the surname include:
Albert Washington McIntire (1853–1935), US Republican politician
Barbara McIntire (1935– ), American golfer
Carl McIntire (1906–2002), a founder and minister in the Bible Presbyterian Church
Harry McIntire (John Reid McIntire) (1879–1949), pitcher for the Brooklyn Superbas
Jim McIntire, U.S. gunfighter, Texas Ranger in the Old West
John McIntire (1759–1815), founder of the city of Zanesville, Ohio
John McIntire (1907–1991), American character actor (films & Wagon Train)
Clifford McIntire (1908– ), US Congressman from Maine
Lani McIntyre aka Lani McIntire (1904–1951), a Hawaiian guitar and steel guitar player
Paul Goodloe McIntire (1860–1952), U.S. stock broker, investor, and philanthropist
Rufus McIntire (1784–1866), U.S. lawyer, congressman
Tim McIntire (1944–1986), American character actor
William Watson McIntire (1850–1912), U.S. Congressman from Maryland