McGlone is a surname. Notable people with the surname include:
Bill McGlone (born 1984), American lacrosse player
Joe McGlone (1896–1963), American football player
John McGlone (1864–1927), American baseball player
Mariam McGlone (1916–2008), American dancer and educator
Mike McGlone (born 1972), American actor and singer
Patsy McGlone, Northern Irish politician
Samantha McGlone (born 1979), Canadian triathlete