McCune is a surname. Notable people with the surname include:
Adam McCune (novelist) (born 1985), American novelist
Alfred W. McCune (b. 1849), British-American railroad builder, mine owner, and Mormon
Barron Patterson McCune (1915–2008), United States federal judge
Debbie McCune Davis (b. 1951), American politician
Emma McCune (1964-1993), British foreign aid worker
Elizabeth Ann Claridge McCune (1852-1924), Mormon missionary
George M. McCune (1908-1948), co-developer of the McCune–Reischauer romanization system of the Korean language
Grant McCune (1943–2010), American special effects designer
Isaac McCune (1884–unknown), Canadian politician
Keith McCune (b. 1955), American author
Lisa McCune (b. 1971), Australian actress
Robert McCune (b. 1979), American football player
Rolland D. McCune (b. 1934), American theologian
Sara Miller McCune (b. 1941) is the co-founder and Chair of SAGE Publications
Shannon Boyd-Bailey McCune (1913-1993), geographer and brother of George M. McCune
William McCune (1953–2011), American computer scientist
