McCollum is a surname. Notable people with the surname include:
Allan McCollum, American artist (1944–present)
Anquell McCollum (born 1973), American college basketball coach
Betty L. McCollum, Minnesota Representative (1954–present)
Ira William "Bill" McCollum, Jr., Florida Congressman (1944–present)
C. J. McCollum, American basketball player
Darius McCollum, obsessive subway buff (1965–present)
Elmer McCollum, biochemist and historian
Miles Parks McCollum, also known as Lil Yachty, American rapper from Atlanta, Georgia
Rick McCollum, painter
Robert McCollum, American voice actor
Ronnie McCollum (born 1978), American professional basketball player
Ruby McCollum, prisoner (died 1954)
Vashti McCollum, plaintiff in landmark U.S. Supreme Court case involving separation of church and state (1912–2006)
