Mayr is a German surname. Notable people with the surname include:
Andrea Mayr (born 1979), Austrian female long-distance runner
Ernst Walter Mayr (1904–2005), German American evolutionary biologist
Georg Mayr (1564–1623), German statistician and economist
Gustav Mayr (1830–1908), Austrian entomologist
Heinz Mayr (born 1935), German racewalker
Johann Simon Mayr (1763–1845), German composer
Karl Mayr (1883–1945), German politician and officer
Michael Mayr (1864–1922), Austrian historian, politician and Bundeskanzler (1920/21)
Rupert Ignaz Mayr (1646–1712), German composer
Simon Marius (1573–1624), German astronomer
Hans Mayr (disambiguation)