Mayo is the given name of:
Mayo Hibi (born 1996), Japanese tennis player
Mayo Methot (1904-1951), American actress, third wife of Humphrey Bogart
Mayo Okamoto (born 1974), Japanese singer-songwriter
Mayo Smith (1915–1977), American baseball player and manager
Mayo Suzukaze (born 1960), Japanese actress
Mayo Thompson (born 1944), American musician and visual artist
Mayo Yamaura (born 1984), Japanese curler