Matsuyama (松山) is a Japanese surname. Notable people with the surname include:
Mitsaharu Matsuyama (松山 光治, 1891–1959), senior officer in the Imperial Japanese Navy during World War II
Kinrey Matsuyama (松山 金嶺, 1900–1953), Japanese billiards player
So Matsuyama (松山 崇, 1908–1977), Japanese production designer and art director
Takashi Matsuyama (actor) (松山 鷹志, born 1960), Japanese actor and voice actor
Kenichi Matsuyama (松山 研, born 1985), Japanese actor
Ryuhei Matsuyama (松山 竜平, born 1985), Japanese baseball player
Hideki Matsuyama (松山 英樹, born 1992), Japanese golfer
