Mathews is a surname. Notable persons with that surname include:
Alfred Augustus Mathews, vicar and Wales international rugby player, 1864-1946
Angelo Mathews (born 1987), Sri Lankan Burgher cricketer
Arthur Mathews (writer), Irish comedy writer
Arthur Frank Mathews, American painter
Bill Mathews, Canadian geologist
Carole Mathews, American actress
Cornelius Mathews, 19th-century American writer
David Mathews, Loyalist mayor of New York, 1776-1783
Eddie Mathews (1931–2001), Hall of Fame third baseman in Major League Baseball
Francine Mathews, American novelist
George Mathews (disambiguation), several people
Gregory Mathews, Australian amateur ornithologist
Harry Mathews (1930–2017), American author
Henry M. Mathews, governor of West Virginia, 1877-1881
James Mathews (disambiguation), several people
Jay Mathews, author, education reporter and online columnist with the Washington Post
Jessica Mathews, president of the Carnegie Endowment for International Peace
Jon Mathews, academic
Jonathan Mathews, baseball coach
Kevin Mathews, Singaporean musician and songwriter
Lloyd Mathews, British naval officer, politician and abolitionist
Marlene Mathews, Australian sprinter
Max Mathews, computer music pioneer
Robert L. Mathews, American football player and coach
Ross Mathews, American television personality
Sampson Mathews, politician, Revolutionary War soldier
Sylvia Mathews Burwell, President of the Global Development Program of the Bill and Melinda Gates Foundation
Thomas Mathews, Royal Navy admiral, 1676-1751
Vera Laughton Mathews, Director of the Women's Royal Naval Service from 1940 until 1946
Walter J. Mathews, American architect
William Mathews (disambiguation), several people
