Masaryk is a Czech surname. Notable people with the surname include:
Tomáš Garrigue Masaryk (1850–1937), Austro-Hungarian and Czechoslovak statesman, sociologist, philosopher, and the first President and founder of Czechoslovakia
Jan Masaryk (1886–1948), Czech diplomat and politician, the son of Tomáš Garrigue Masaryk
Alice Masaryk (1879–1966), Czech sociologist and one of the founding members of the Czechoslovak Red Cross, the daughter of Tomáš Garrigue Masaryk
Pavol Masaryk (born 1980), Slovak football striker
Fritzi Massary (born Massaryk)