EC number 5.4.99.53 BRENDA BRENDA entry KEGG KEGG entry | IntEnz IntEnz view ExPASy NiceZyme view MetaCyc | |
Marneral synthase (EC 5.4.99.53) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, marneral-forming). This enzyme catalyses the following chemical reaction
(3S)-2,3-epoxy-2,3-dihydrosqualeneMarneral is a triterpenoid formed by Grob fragmentation of the A ring of 2,3-epoxy-2,3-dihydrosqualene during cyclization. This aldehyde gains its name from its structural similarity to a class triterpenes commonly found in members of the Iridaceae, originally identified by Dr. Franz-Josef Marner.
This enzyme is a member of a metabolic gene cluster along with two other cytochrome P450s.
References
Marneral synthase Wikipedia(Text) CC BY-SA