Marchetti is an Italian surname. Notable people with the surname include:
Alberto Marchetti (born 1954), Italian professional football player
Alessandro Marchetti (aircraft engineer) (1884–1966), Italian aircraft engineer
Alessandro Marchetti (mathematician) (1633–1714), Italian mathematician
Assunta Marchetti (1871–1948), Italian beatified of catholic church
Elio Marchetti (born 1974), Italian race car driver and motorcycle racer
Federico Marchetti (born 1983), Italian international football goalkeeper
Filippo Marchetti (1831–1902), Italian opera composer
Gino Marchetti (born 1927), American professional football player
John W. Marchetti (1908-2003), radar pioneer
Louis Marchetti (1920–1992), Italian illustrator and portrait painter
Marco Marchetti (1528–1588), Italian painter of the late-Renaissance or Mannerist period
Victor Marchetti (born 1930), American intelligence agent and director in the CIA
