EC number 4.2.1.8 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9024-31-1 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a mannonate dehydratase (EC 4.2.1.8) is an enzyme that catalyzes the chemical reaction
D-mannonateHence, this enzyme has one substrate, D-mannonate, and two products, 2-dehydro-3-deoxy-D-gluconate and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include mannonic hydrolase, mannonate hydrolyase, altronic hydro-lyase, altronate hydrolase, D-mannonate hydrolyase, and D-mannonate hydro-lyase. This enzyme participates in pentose and glucuronate interconversions.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1TZ9.