Manfredi is a surname of Italian origin. The name may refer to:
Persons
Manfredi family, a noble family, lords of Faenza, Italy
Manfredi (1232–1266), King of Sicily
Barbara Manfredi (1444–1466), Italian wife of Pino III Ordelaffi, lord of Forlì
Bartolomeo Manfredi (1582–1622), Italian painter; a leading member of the Caravaggisti
Christopher Manfredi (contemporary), Canadian professor of political science
Ercole Manfredi (1883–1973), Italian architect who worked in Siam (Thailand)
Juan J. Manfredi (b. 1957), mathematician
Laurence Manfredi (b. 1974), French Olympic shot putter
Nino Manfredi (1921–2004), Italian actor
Raphael Manfredi (b. 1968), French software engineer
Valerio Massimo Manfredi (b. 1946), Italian architect and historian
Fictional characters
Kate Manfredi, character in the Australian television series McLeod's Daughters
