Manes, Mánes or Mánes is a surname. Notable people with the surname include:
Antonín Mánes (1784-1843), Czech painter
Donald R. Manes (1934-1986), borough president of Queens, New York
Édouard Manès (1835-1898), governor general of French India
Gina Manès (1893-1989), French film actress
Josef Mánes (1820-1871), Czech painter
Pablo Curatella Manes (1891-1963), Argentine painter
Quido Mánes (1828-1880), Czech painter