Mandelbaum is a surname. Notable people with the surname include:
Allen Mandelbaum (born 1926), American professor of Italian literature, poet, and translatorFredericka Mandelbaum (1818–1894), New York entrepreneur and criminal fence operatorFrederic Morton (born Fritz Mandelbaum) (born 1924), Austrian writerHenryk Mandelbaum (1922–2008), holocaust survivorJacques Mandelbaum (born 1958), French journalist and film criticJoel Mandelbaum (born 1932), microtonal musicianKen Mandelbaum, American columnist, critic, and authorKurt Mandelbaum, development economist (1905-1995)Michael Mandelbaum, professor of American foreign policySamuel Mandelbaum (1884–1946), American lawyer and politician