Manchester score

Updated on Dec 04, 2023

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Manchester score is an indicator of prognosis in small cell lung cancer. It is calculated from a number of physical and biochemical markers.

A patient with small cell lung cancer scores one point for each of the following: -

Serum lactate dehydrogenase exceeds the upper limit of the reference range.

Serum sodium concentration less than 132 mmol/l.

Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.

Serum bicarbonate less than 24.

Karnofsky performance status less than 60.

Extensive stage disease.

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