Manchester North End F.C. was an association football club based in Manchester, England. The club was founded in 1922 as New Cross F.C. and joined the Lancashire Combination, before changing its name the following year. In the 1924–25 season, Manchester North End left the Lancashire Combination and entered the Cheshire County League, where they remained until 1939, when the club folded. The club reformed under the name North End FC in 2011 before changing their name to Manchester North End FC in 2016.
Manchester North End currently play in the Manchester Saturday Morning League, Division two.
During the club's existence, Manchester North End participated in the FA Cup, England's foremost cup competition, on several occasions, reaching the fourth qualifying round twice.