Mamie is a feminine given name and nickname (often of Mary) which may refer to:
Given name:
Mamie Clark (1917–1983), African American psychologist
Mamie Eisenhower (1896–1979), wife of President Dwight D. Eisenhower
Mamie Johnson (1935–), first female pitcher in the Negro Leagues
Mamie Locke (1954–), Democratic member of the Virginia Senate
Mamie Smith (1883–1946), American vaudeville singer, dancer, pianist and actress
Mamie Thurman (1901–1932), American murder victim
Nickname:
Mary Mamie Cadden (1891–1959), Irish midwife, backstreet abortionist and convicted murderer
Mary Dickens (1838–1896), daughter of Charles Dickens
Marion Graves Anthon Fish (1853–1915), American socialite
Mary Mamie Gummer (1983–), American actress
Mary Mamie Lincoln (1869–1938), granddaughter of Abraham Lincoln
Stage name:
Mamie Jones, pseudonym of American singer Aileen Stanley (1897–1982)
Mamie Van Doren (1931–), American actress and sex symbol born Joan Lucille Olander
Fictional characters:
Mamie Dubcek, from the NBC sitcom 3rd Rock from the Sun
Mamie Johnson, in the CBS soap opera The Young and the Restless
the title character of The Revolt of Mamie Stover, a 1951 novel by William Bradford Huie
