EC number 5.2.1.2 ExPASy NiceZyme view | CAS number 9023-75-0 | |
In enzymology, a maleylacetoacetate isomerase (EC 5.2.1.2) is an enzyme that catalyzes the chemical reaction
4-maleylacetoacetate
Hence, this enzyme has one substrate, 4-maleylacetoacetate, and one product, 4-fumarylacetoacetate.
This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 4-maleylacetoacetate cis-trans-isomerase. Other names in common use include maleylacetoacetic isomerase, maleylacetone isomerase, and maleylacetone cis-trans-isomerase. This enzyme participates in tyrosine metabolism and styrene degradation.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1FW1, 2CZ2, and 2CZ3.
References
Maleylacetoacetate isomerase Wikipedia(Text) CC BY-SA