Malacarne is an Italian surname. Notable people with the surname include:
Davide Malacarne (born 1987), Italian cyclistJuliana Malacarne (born 1974), American physique competitorLucas Malacarne (born 1988), Argentine footballerPaolo Malacarne (born 1947), Italian sprint canoeistSimone Malacarne (born 1989), Italian footballerMarco Malacarne (born 1956), European Commission high-ranking official