Major is a surname. Notable people with the surname include:
Bobby Majors (born 1949), American football player
Clarence Major (born 1936), American poet
Edward Major (1615–ca. 1655), Virginia colonial politician
Fali Homi Major (born 1947), Indian air marshal
Gerri Major (1894–1984), African-American journalist and community leader
John Major (born 1943), former Prime Minister of the United Kingdom
John C. Major (born 1931), Canadian jurist
John Clarkson Major (1826–1895), English manufacturing chemist and tar distiller, mayor of Wolverhampton 1875–76
Johnny Majors (born 1935), American football player and coach
Lee Majors (born 1939), American actor
Léo Major (1921–2008), Canadian Army corporal
Les Major (1926–2001), English footballer
Mark Major (born 1970), Canadian ice hockey player
Shirley Majors (1914–1981), American football coach, father of Johnny Majors
Thomas Major (1720–1799), English engraver
William James Major (1881–1953), Canadian politician and jurist
William T. Major (1790–1867), American pastor