Maine is a surname. Notable people with the surname include:
Charles Eric Maine (1921–1981), pen name of David McIlwain, English writer
Henry James Sumner Maine (1822–1888), British legal historian
John Maine (born 1981), American baseball player
Mack Maine (born 1985), American rapper and singer
Scott Maine (born 1985), American baseball player
Fictional characters:
Norman Maine, a fictional character in the 1937 film A Star Is Born and the 1954 remake