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Magnesium protoporphyrin IX monomethyl ester (oxidative) cyclase

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EC number
  
1.14.13.81

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
92353-62-3

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (EC 1.14.13.81, Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase) is an enzyme with systematic name magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating) . This enzyme catalyses the following chemical reaction

magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 ⇌ divinylprotochlorophyllide + 3 NADP+ + 5 H2O (overall reaction) (1a) magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 ⇌ 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1b) 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 ⇌ 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O (1c) 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 ⇌ divinylprotochlorophyllide + NADP+ + 2 H2O

This enzyme requires Fe(II) for activity.

References

Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase Wikipedia
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