Harman Patil (Editor)

Mafosfamide

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Formula
  
C9H19Cl2N2O5PS2

Classification
  
Sulfonic acid

Molar mass
  
401.269 g/mol

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Mafosfamide meaning


Mafosfamide (INN) is an oxazaphosphorine (cyclophosphamide-like) alkylating agent under investigation as a chemotherapeutic. It is metabolized by cytochrome P450 into 4-hydroxycyclophosphamide, which is then converted into aldophosphamide, which, in turn yields the cytotoxic metabolites phosphoramide mustard and acrolein.

Several Phase I trials have been completed.

References

Mafosfamide Wikipedia