Madras motor neuron disease

Madras motor neuron disease is a form of motor neuron disease closely related to the Brown-Vialetto-Van Laere and Boltshauser syndromes.

Characteristic features of this disease include facial and bulbar paralysis, sensorineural hearing impairment, asymmetrical weakness of limbs and pyramidal signs with a slow progression. Its variants have additional features including optic atrophy and cerebellar signs.