Mack is a surname. Notable people with the surname include:
Allison Mack (born 1982), American actor best known for her role in Smallville
Andrew Mack (1780–1854), mayor of Detroit in 1834
Andrew Mack (actor) (1863–1931), American actor and songwriter
Betty Mack (1901–1980), American film actress
Bill Mack, country music radio host
Burton L. Mack, American theologian
Cecil Mack (1883–1944), American composer, lyricist and music publisher
Chris Mack (disambiguation), various people
An American family that started in baseball and has moved into politics:
Connie Mack (1862–1956), baseball player, executive, and team owner
Earle Mack (1890–1967), Connie's son; baseball player
Connie Mack III (born 1940), grandson of Connie and nephew of Earle; politician
Connie Mack IV (born 1967), son of Connie III; politician
Mary Bono Mack (born 1961), wife of Connie IV; politician and widow of Sonny Bono
Craig Mack (born 1971), American rap musician
David Alan Mack, writer best known for his freelance Star Trek novels
David S. Mack, American businessman
Denny Mack (1851–1888), baseball player
Earle I. Mack (born 1938), businessman and former US Ambassador
Ebenezer Mack (1791–1849), New York politician
Elbert Mack (born 1986), American football cornerback
Eugen Mack (1907–1978), Swiss gymnast and Olympic Champion
H. Bert Mack (1912-1992), American real estate developer
Hans-Joachim Mack (1928–2008), German general
Helen Mack (1913–1986), American actress
Jerome D. Mack (a.k.a. Jerry Mack) (1920-1998) was an American banker, real estate investor, political fundraiser and philanthropist in Las Vegas, Nevada.
Jimmy Mack (broadcaster) (1934–2004), Scottish radio and television presenter
Joe Mack (disambiguation), various people
John E. Mack (1929–2004), American psychiatrist, writer, and professor at Harvard Medical School
John J. Mack (born 1944), CEO of Morgan Stanley
John M. Mack (aka Jack Mack) (born 1864, d 1924) Founder Mack Trucks.
Karen Mack, American television producer for CBS and co-author of three novels from Los Angeles, California.
Karl Mack von Leiberich (1752–1828), Austrian general, famous for his defeat at Ulm in Napoleon's campaign of 1805
Kevin Mack, see Kevin Mack (disambiguation)
Khalil Mack, American football player
Lee Mack (born 1968), the stage name for English stand-up comedian Lee Gordon McKillop.
Lonnie Mack (1941–2016), American rock and blues guitarist/vocalist
Nate Mack (1891-1965), Polish-born American banker; co-founder of the Bank of Las Vegas.
Norman Edward Mack (1855–1932), editor and publisher of the Buffalo Daily Times
Oliver Mack (born 1957), retired American professional basketball player
Peter F. Mack, Jr. (1916–1986), former U.S. politician
Red Mack (born 1937), American football wide receiver and halfback
Reinhold Mack, record producer known for working with Electric Light Orchestra, Queen and other rock bands
Rico Mack (born 1971), American football player
Rodney Mack, ring name of professional wrestler Rodney Begnaud
Ronnie Mack (1940–1963), American songwriter
Sam Mack (born 1970), retired American professional basketball player
Shane Mack (baseball) (born 1963), former left and center fielder
Shane Mack (mayor) (born 1969)
Sherman Q. Mack (born 1972), Louisiana politician
Shorty Mack (born 1981), international rapper and actor
Steve Mack (born 1979), American professional wrestler, better known by his ring name Monsta Mack
Tara Mack (born 1983), Minnesota politician and a member of the Minnesota House of Representatives
Ted Mack (radio-TV host) (1904–1976), host of Ted Mack and the Original Amateur Hour on radio and television
Timothy Mack (born 1972), American pole vaulter and Olympic champion
Tom Mack (born 1943), former left guard
Wayne Mack, sportscaster
Willard Mack (1873–1934), Canadian-born actor, director, and playwright
Fictional characters:
The title character for the 1990s show The Secret World of Alex Mack
Mark Mack, character in the HBO series Oz