Macdowall is a surname. Notable people with the surname include:
Alex MacDowall (born 1991), British auto racing driver
Clan Macdowall, Scottish clan
Day Hort MacDowall (1850–1927), politician from old Northwest Territories, Canada
Duncan MacDowall (born 1963), English former professional footballer
Robert Holford Macdowall Bosanquet (1841–1912), English scientist and music theorist
William MacDowall, Scottish priest and Master of Works to Mary, Queen of Scots and her mother Mary of Guise