Trisha Shetty (Editor)

MYLK4

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Symbol
  
MYLK4

HUGO
  
27972

UniProt
  
Q86YV6

Entrez
  
340156

RefSeq
  
NM_001012418

EC number
  
2.7.11.18

MYLK4

Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene. MYLK4 is a member of the myosin light-chain kinase family of serine/threonine-specific protein kinases that phosphorylate the regulatory light chain of myosin II.

This protein acts as an enzyme that catalyzes the following reaction: ATP + a protein -> ADP + a phosphoprotein.

MYLK4 is also involved in protein amino acid phosphorylation meaning that it adds a phosphate group onto the molecule.

Not very much is known about the specific functional characteristics of MLYK4, but it has recently been found that the gene may possibly have a role in having at least one driver mutation for cancer. MYLK4 may also be involved in transferase activity, ATP binding, protein serine/threonine kinase activity, and also nucleotide binding. Other names for MYLK4 are CaMLCK like; EG238564; MYLK4; Mylk4; Myosin light chain kinase family, member 4; SgK085; SGK085; Sgk085; Sugen kinase 85; Uncharacterized serine/threonine-protein kinase SgK085.


There are other known myosin light-chain kinase enzymes.

References

MYLK4 Wikipedia