Species Human Entrez 64983 | Human Mouse Ensembl ENSG00000106591 | |
Aliases MRPL32, L32mt, MRP-L32, bMRP-59b, HSPC283, mitochondrial ribosomal protein L32 External IDs MGI: 2137226 HomoloGene: 32711 GeneCards: MRPL32 |
39S ribosomal protein L32, mitochondrial is a protein that in humans is encoded by the MRPL32 gene.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp.