Species Human Entrez 112609 | Human Mouse Ensembl ENSG00000135324 | |
Aliases MRAP2, BMIQ18, C6orf117, bA51G5.2, melanocortin 2 receptor accessory protein 2 External IDs MGI: 3609239 HomoloGene: 16307 GeneCards: MRAP2 | ||
Melanocortin 2 receptor accessory protein 2 is a protein that in humans is encoded by the MRAP2 gene. MRAP2 interacts directly with melanocortin 4 receptor (MCR4).
Knockout of the Mrap2 gene in mice leads to severe obesity. In addition, a rare mutation of the MRAP2 gene in humans leads to severe, early-onset obesity.
References
MRAP2 Wikipedia(Text) CC BY-SA