Supriya Ghosh (Editor)

MMS22L

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Species
  
Human

Entrez
  
253714

Human
  
Mouse

Ensembl
  
ENSG00000146263

Aliases
  
MMS22L, C6orf167, dJ39B17.2, MMS22 like, DNA repair protein

External IDs
  
MGI: 2684980 HomoloGene: 18874 GeneCards: MMS22L

Methyl methanesulfonate-sensitivity protein 22-like also known as MMS22-like, DNA repair protein is a protein that in humans is encoded by the MMS22L gene.

Model organisms

Model organisms have been used in the study of MMS22L function. A conditional knockout mouse line, called Mms22ltm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty six tests were carried out on mutant mice and two significant abnormalities were observed. No homozygous mutant embryos were identified during gestation, and therefore none survived until weaning. The remaining tests were carried out on heterozygous mutant adult mice; no additional significant abnormalities were observed in these animals.

References

MMS22L Wikipedia