Species Human Entrez 4284 | Human Mouse Ensembl ENSG00000135517 | |
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Aliases MIP, AQP0, CTRCT15, LIM1, MIP26, MP26, major intrinsic protein of lens fiber External IDs MGI: 96990 HomoloGene: 40627 GeneCards: MIP | ||
Lens fiber major intrinsic protein is a protein that in humans is encoded by the MIP gene.
Function
Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13.
References
MIP (gene) Wikipedia(Text) CC BY-SA