Species Human Entrez 57534 | Human Mouse Ensembl ENSG00000101752 | |
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Aliases MIB1, DIP-1, DIP1, LVNC7, MIB, ZZANK2, ZZZ6, mindbomb E3 ubiquitin protein ligase 1 External IDs MGI: 2443157 HomoloGene: 10810 GeneCards: MIB1 | ||
MIB1 marker also used for detection of grades of astrocytoma
E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene. It is involved in regulating apoptosis.
Confusion with proliferative marker
An antibody directed at the protein Ki-67, a product of the MKI67 gene, is called MIB-1. The MIB1 gene, which regulates apoptosis, should not be confused with the MIB-1 antibody, which is used to measure Ki-67 expression.
References
MIB1 (gene) Wikipedia(Text) CC BY-SA