MDA MB 468

MDA-MB-468 is a cell line that was isolated from a 51 year old female human in 1977, and commonly used in cancer research. These cells were extracted from pleural effusion of mammary gland/breast tissue and have proven useful for the study of metastasis, migration and invasion of breast cancer. The cell line was isolated in 1977 by R. Cailleau, et al., from a pleural effusion of a 51-year-old Black female patient with metastatic adenocarcinoma of the breast. Although the tissue donor was heterozygous for the G6PD alleles, the cell line consistently showed only the G6PD A phenotype.