Species Human Entrez 4168 | Human Mouse Ensembl ENSG00000101977 | |
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Aliases MCF2, ARHGEF21, DBL, MCF.2 cell line derived transforming sequence External IDs MGI: 96932 HomoloGene: 3917 GeneCards: MCF2 | ||
Proto-oncogene DBL is a protein that in humans is encoded by the MCF2 gene.
MCF2 is a member of a large family of GDP-GTP exchange factors that modulate the activity of small GTPases of the Rho family. Five-prime recombinations result in the loss of N-terminal codons, producing MCF2 variants with oncogenic potential.[supplied by OMIM]
References
MCF2 Wikipedia(Text) CC BY-SA