Symbol MBOAT Pfam clan CL0517 Pfam structures | Pfam PF03062 InterPro IPR004299 PDB RCSB PDB; PDBe; PDBj | |
The MBOAT (membrane bound O-acyl transferase) family of membrane proteins is a family of various acyltransferase enzymes. All family members contain multiple transmembrane domains and most carry two conserved residues which might be active-site residues, a conserved histidine (His) embedded in a hydrophobic stretch of residues and an asparagine (Asn) or histidine within a more hydrophilic region some 30-50 residues upstream.
MBOAT enzymes catalyze the transfer of an acyl group from acyl-coenzyme to one of several different substrates. The family is found from bacteria to eukaryotes, and the active region lies outside the membrane.
The family may be grouped into four categories, according to function:
References
MBOAT Wikipedia(Text) CC BY-SA